Gut bacteria toxin linked to worse clinical outcomes in patients with alcoholic liver disease; treatment with bacteriophages clears the bacteria and eliminates the disease in mice
Researchers at Columbia University were able to grow fully functional lungs in mouse embryos using transplanted stem cells. The findings suggest that it may be ultimately possible to use the technique to grow human lungs in animals for patients who need transplants and to study new lung treatments.
Species-specific Liver-Chip could improve success rate of drug candidates in clinical trials
The protein adipsin, which is produced in body fat, helps protect insulin-secreting cells called pancreatic beta cells from destruction in type 2 diabetes, according to a new study by researchers at Weill Cornell Medicine and NewYork-Presbyterian. Among middle-aged adults, higher levels of the protein in the blood were also associated with protection from type 2 diabetes.
Insulin which is released by pancreatic beta-cells is the main regulator of blood sugar. Previous and current studies by a research group at Lund University in Sweden have identified around hundred different receptors on the surface of the beta-cells, with a diverse functional impact on the beta-cells.