Circulation: Cardiovascular Quality and Outcomes Journal Report
Some of the longevity that appears to run in families can instead be attributed to people choosing life partners with similar characteristics.
Want to be a supercentenarian? The chances of reaching the ripe old age of 110 are within reach – if you survive the perilous 90s and make it to 105 when death rates level out, according to a study of extremely old Italians led by UC Berkeley and Sapienza University of Rome.
Physical and mental exercise is not only beneficial for your own brain, but can also affect the learning ability of future offspring – at least in mice. This particular form of inheritance is mediated by certain RNA molecules that influence gene activity.
Scientists discover that nucleolar size correlates with health and lifespan in organisms as diverse as roundworms, flies and humans
The longest lived laboratory mice, more than a decade after the creation of the first lineage, are still those with impaired growth hormone signaling. That record has yet to be overtaken, and I suspect that it may well stand unbroken until the development of rejuvenation therapies based on damage repair is further advanced, and senescent cell clearance is joined by other types of therapy, their effects adding together. Thus growth hormone and growth hormone receptor genes in humans are one of the places to look for variants and mutations that might improve our understanding of how metabolism influences aging, and as a bonus for those interested in pharmacological or genetic adjustment of metabolism, may lead to ways to modestly slow aging.