Young, resting neural stem cells have large protein clumps often associated with neurodegeneration. As stem cells age, the aggregates inhibit their ability to make new neurons, Stanford researchers say.
Multi-resistent microbes are a growing danger. The often unnecessary and mass use of antibiotics causes the impassivity of pathogens against drugs. Infections that were easily curable up to now, may become life threatening.
Researchers have fused living and non-living cells for the first time in a way that allows them to work together, paving the way for new applications.
Stem cells are considered to be immortal in culture and, therefore, of great interest for aging research. This immortality is regulated by increased proteostasis, which controls the quality of proteins. A team of researchers led by David Vilchez of the Cluster of Excellence CECAD at the University of Cologne found a link between increased proteostasis and immortality of human embryonic stem cells. Their results are published in the online research journal ‘Scientific Reports’.