Science and Health News

Freiburg researchers find that an antimicrobial molecule modifies T-cell-signalling and thus attenuates overshooting immune reactions

The clinical trial began in 2019 and involved 3,900 volunteers.

Researchers in the United States and Japan have discovered a new mechanism that links age-related cartilage tissue stiffening with the repression of a key protein associated with longevity. These findings enhance the understanding of mechanisms that lead to the deterioration of joints that causes osteoarthritis, according to the authors of a new study, published January 10th in Nature Communications.

Cambridge scientists have successfully trialled an artificial pancreas for use by patients living with type 2 diabetes. The device – powered by an algorithm developed at the University of Cambridge – doubled the amount of time patients were in the target range for glucose compared to standard treatment and halved the time spent experiencing high glucose levels.

Research reveals how the drugs target an enzyme involved in lowering blood sugar.

The male reproductive system serves as a hotspot for the emergence of new genes. Perhaps that explains why more new mutations are inherited from fathers than from mothers. It doesn’t, however, clarify why older fathers pass on more mutations than younger ones do.

A large-scale Phase 3 clinical trial to establish ambroxol’s potential to slow the progression of Parkinson’s disease, will start in early 2023.

For chronic conditions such as rheumatoid arthritis, treatment often involves lifelong injections. Fear of needles, injection-associated infection and pain are responsible for patients skipping doses, which encourages the development of new delivery strategies that combine efficacy with limited side effects to treat patients adequately.