Bernhard Baumann, Adelheid Woehrer, Gabor G. Kovacs, Christoph K. Hitzenberger et al.
Description of the technology
One major hallmark of Alzheimer’s disease (AD) and cerebral amyloid angiopathy (CAA) is the deposition of extracellular senile plaques and vessel wall deposits composed of
This technology provides polarization sensitive optical coherence microscopy (
The technology is highly promising as a diagnostic method for assessing the progression of Alzheimer’s disease on the basis of the state and development of neuritic plaques in the vessels of the brain. The method is suitable for use in practical medicine and experimental researches.
- Medical University of Vienna, Center for Medical Physics and Biomedical Engineering, Vienna (Austria)
- General Hospital and Medical University of Vienna, Institute of Neurology, Vienna (Austria)
- General Hospital and Medical University of Vienna, Department of Biomedical Imaging and
Image-guidedTherapy, Vienna (Austria)
- Baumann, B. et al. «Visualization of neuritic plaques in Alzheimer’s disease by
polarization-sensitiveoptical coherence microscopy." 7 Scientific Reports (2017): 43477.
- Pircher, M., Hitzenberger, C. K. &
Schmidt-Erfurth, U. «Polarization sensitive optical coherence tomography in the human eye." 30 Prog. Retin. Eye Res. (2011): 431–451.
- Götzinger, E. et al. «Polarization maintaining fiber based
ultra-highresolution spectral domain polarization sensitive optical coherence tomography." 17 Opt. Express (2009): 22704–22717.