Prana Biotechnology

The Company's lead drug candidate – PBT2 – is being developed for the treatment of Alzheimer’s and Huntington's diseases. The Company is targeting lodgement of a New Drug Application for Huntington's disease in 2016/2017 pending positive trial results.

Prana Biotechnology also has advanced a drug candidate for Parkinson’s disease and other movement disorders (PBT434) and brain cancer (PBT519), which are in pre-clinical toxicology testing. Development of PBT434 has received funding from the Michael J. Fox Foundation and Parkinsons UK.

The Company has a library of more than 1000 Metal Protein Attenuating Compounds (MPACs) which may support new therapies for neurodegenerative disease and other highly prevalent conditions. Other potential applications for this platform technology include specific cancers.

The earliest beginnings of Prana Biotechnology began in the laboratory of Professor Rudolph Tanzi at Massachusetts General Hospital in the 1980s when he was investigating the molecular and genetic basis of neurological disease.