A mutation in the small protein SHMOOSE is associated with Alzheimer’s risk and highlights a possible target for treatment.
Infections treated with specialty hospital care in early- and mid-life are associated with an increased subsequent risk of Alzheimer’s and Parkinson’s diseases, but not amyotrophic lateral sclerosis (ALS), according to a study by researchers from Karolinska Institutet, published in PLOS Medicine.
With a $45 million grant from the National Institutes of Health and National Institute on Aging, the Alzheimer’s Disease Cooperative Study (ADCS) at University of California San Diego, in collaboration with Burke Neurological Institute (BNI) and Columbia University Irving Medical Center, will launch a nationwide clinical trial to further investigate the therapeutic potential of benfotiamine, a synthetic version of thiamine (B1), as a metabolic treatment approach to Alzheimer’s disease.
A novel, disease-modifying therapy for Alzheimer’s disease may involve the whole exchange of blood, which effectively decreased the formation of amyloid plaque in the brains of mice, according to a new study from UTHealth Houston.
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia, affecting more than 5.8 million individuals in the U.S.
A new mouse study reveals a breakdown in the process that clears brain cells of waste products precedes the buildup of amyloid plaques associated with Alzheimer’s disease.