The New England Journal of Medicine (NEJM.org) is dedicated to bringing physicians the best research and key information at the intersection of biomedical science and clinical practice, and to presenting the information in an understandable and clinically useful format. A career companion for physicians, NEJM keeps practicing physicians informed on developments that are important to their patients and keeps them connected to both clinical science and the values of being a good physician. NEJM employs a highly rigorous peer-review and editing process to evaluate manuscripts for scientific accuracy, novelty, and importance. The editors have set policies to ensure that authors disclose all relevant financial associations and that those financial associations do not influence published content. These factors contribute to NEJMТs reputation as the «gold standard» for quality biomedical research and for the best practices in clinical medicine. NEJM is the most widely read, cited, and influential general medical periodical in the world. As it evolves to meet the changing needs of its readers in the 21st century, it is committed to maintaining that reputation and integrity, while using innovative formats and technologies for new features and faster delivery and access.