Alzheimer's disease progressively degrades a person's memory and cognitive abilities, often resulting in dementia. Amid efforts to find novel treatments for this disease, a recent breakthrough study by scientists from Japan shows that oxytocin―the hormone that we commonly know to induce feelings of love and well-being―can also effectively reverse some of the damage caused by amyloid plaques in the learning and memory center of the brain in an animal model of Alzheimer's.
When tested in brain cells and in a mouse model of Alzheimer’s disease, a new compound significantly reduced the number of amyloid plaques in the brain, lessened brain inflammation and diminished other molecular markers of the disease.
A Georgetown University Medical Center clinical trial investigating the cancer drug nilotinib in people with Alzheimer’s disease finds that it is safe and well-tolerated, and researchers say the drug should be tested in a larger study to further determine its safety and efficacy as a potential disease-modifying strategy.
In the presence of alcohol, a defective version of the aldehyde dehydrogenase 2 gene in human cell cultures and mice leads to biochemical changes associated with Alzheimer’s disease.
Home for the holidays – but will grandpa remember me? Now there’s hope; Hebrew University team finds tb vaccine lowers rates of Alzheimer’s disease in cancer patients.