In the presence of alcohol, a defective version of the aldehyde dehydrogenase 2 gene in human cell cultures and mice leads to biochemical changes associated with Alzheimer’s disease.
Home for the holidays – but will grandpa remember me? Now there’s hope; Hebrew University team finds tb vaccine lowers rates of Alzheimer’s disease in cancer patients.
Neuroscientists at Georgetown University Medical Center say they have developed and tested an agent that reduces the buildup of toxic proteins in animal models of both Parkinson’s and Alzheimer’s diseases, and improves cognitive and motor behavior.
A team of scientists from the Moscow Institute of Physics and Technology (MIPT) and Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry (IBCh RAS) studied one hereditary genetic mutation to discover general molecular mechanisms that may lead both to early onset of Alzheimer’s disease and to the form of the disease caused by age-related changes in human body.
UB researchers’ insights into a target that succeeded in animals but failed in humans reveal a new paradigm for screening Alzheimer’s drugs
The risk of developing Alzheimer’s disease increases with age. Susanne Wegmann of the German Center for Neurodegenerative Diseases (DZNE) in Berlin and colleagues have uncovered a possible cause for this connection:Certain molecules involved in the disease, termed tau-proteins, spread more easily in the aging brain.